Kumarin (2H-chromene-2one ya 2H-1-benzopyranon-2) — lactone o-hydroxycinnamic turşusu.

Kumarin
Molekulyar modelin şəkli
Ümumi
Kimyəvi formulu C₉H₆O₂[1]
Molyar kütlə 146,14 q/mol
Fiziki xassələri
Sıxlıq 0,935 q/sm³
Termik xüsusiyyətlər
Ərimə nöqtəsi 71 °S
Qaynama nöqtəsi 301 °S
Təsnifatı
CAS-da qeyd. nöm. 91-64-5
PubChem
SMILES C1=CC=C2C(=C1)C=CC(=O)O2
RTECS GN4200000
ChEBI 28794
ChemSpider

Xüsusiyyətləri

redaktə

Yeni kəsilmiş otların qoxusunu verən rəngsiz kristallardır; ərimə temperaturu 70 ° C, qaynama temperaturu 291 ° C-dir. Kumarin spirt və efirdə yaxşı, suda zəif həll olur ,4-hidroksillə yüngül turşu xassəsi göstərdiyi üçün, bir qədər qələvi mühitdə həll edilə bilər.

Kimyəvi xassələr

redaktə

Kumarin benzoldan fərqli olaraq doymamış laktonlar və ya benzoləvəzləyicilərlə daha az reaksiya qabiliyyətinə malikdir. A

Təbiətdə olması

redaktə

Kumarin glikosidlər şəklində bir çox bitkilərin tərkibində aşkar edilmişdir - onların nümayəndələri arasında Astrov ailə ( gerbera, chamomile, civanperçemi ), eləcə də yonca, bizon, darçını göstərmək olar.

Alınması

redaktə

Sənayedə coumarin salisilik aldehid və asatik anhidritdən əldə edilir (bax) Perkin reaksiya ).

Tətbiqi

redaktə

Kumarindən tütün məhsullarının istehsalında və ətir sənayesində istifadə olunur. Törəmələridən (coumarins) boya lazerlərində istifadə olunur. Qalvanika sənayesində də güclü parlayıcı kimi istifadə olunur. Kumarinin bir insana fizioloji təsiri çox zəifdir. Bununla birlikdə, coumarin müxtəlif bitkilər üzərində nəzərə çarpacaq dərəcədə təsir göstərir. Koumarin törəmələrində fizioloji təsiri daha qabarıqdır. Məsələn, coumarin-3-karboksilik turşusu törəmələri hipnotikdir. Dikumarol (3,3'-metilen-bis-4-hidroksikumarin) qan laxtalanmasına müdaxilə edir.

Mənbə

redaktə
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İstinadlar

redaktə
  1. coumarin (ing.).